ea0038oc5.4 | Thyroid and parathyroid | SFEBES2015
Watkins Rachel
, Imruetaicharoenchoke Waraporn
, Sharma Neil
, Gentillin Erica
, Bosseboeuf Emy
, Kwan Perkin
, Fletcher Rachel
, Mehanna Hisham
, Boelaert Kristien
, Read Martin
, Smith Vicki
, McCabe Christopher
Metastasis is a multistep process responsible for the majority of endocrine cancer deaths. Central to the ability of cells to move is the recruitment of actin fibres at the periphery of the cell by key proteins, especially the cortical actin binding protein cortactin. A full understanding of cortactin function is required in order to address metastatic cell activity within endocrine cancer. We used IP-MS to discover protein binding partners, and now identify the proto-oncogene...